KMID : 0390620080160010017
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Journal of Cardiovascular Ultrasound 2008 Volume.16 No. 1 p.17 ~ p.22
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Echocardiographic Plains Reflecting Total Amount of Epicardial Adipose Tissue as Risk Factor of Coronary Artery Disease
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Hwang Jung-Won
Yoon Myeong-Ho Hwnag Gyo-Seung Tahk Seung-Jea Shin Joon-Han Kang Doo-Kyoung Choi Un-Jung Ahn Sung-Gyun Lim Hong-Seok Kang Soo-Jin Choi Byoung-Joo Choi So-Yeon
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Abstract
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Background: Several studies suggested that epicardial adipose tissue (EAT) might be associated with metabolic syndrome and coronary atherosclerosis. But, little had been studied whether the thickness of EAT on echocardiography could represent the whole amount of EAT. The purpose of this study was to identify the best echocardiographic methods reflecting total amount of EAT.
Methods: Sixty subjects (32 women, mean: 58¡¾12 years-old) who underwent 64-slice multidetector computed tomography (MDCT) were consecutively enrolled. All CT scanning was performed one Brilliance CT-64-channel configuration scanner (Philips, Cleveland, USA) and axially contiguous 10-mm-thickeness sections were obtained from aortic valve to diaphragm level. EAT area was manually traced in each slice and summed up. The EAT thickness was measured as the echo-lucent or echo-dense space between epicardium and pericardium at parasternal long-axis, modified 4-chamber, and apical 4-chamber view.
Results: The EAT thickness at parasternal long-axis and modified 4-chamber view and the sum of EAT thickness from each views (median thickness: 1.0, 2.8, 1.1 and 5.0 mm, respectively) were all correlated with total EAT area on MDCT. Among echo parameters, the EAT thickness measured on parasternal long-axis view during diastole correlated best with total EAT area on MDCT (r=0.572, p£¼0.001).
Conclusion: The echocardiographic EAT measurement might be easily accessible and less harmful method representing whole amount of EAT. The measurement of the thickness of EAT on parasternal long-axis view during diastole by echocardiography might be feasible and reliable in the studying field of EAT.
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KEYWORD
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Epicardial adipose tissue, Echocardiography, Multidetector computed tomography (MDCT)
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